Effects of direct therapeutic radiation on pulpal surface of root dentin: an in vitro study

DENİZ Y., Işıktaş Acar E., ÇETİN GENÇ Ç.

Radiation and Environmental Biophysics, cilt.62, sa.2, ss.261-268, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 2
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1007/s00411-023-01020-9
  • Dergi Adı: Radiation and Environmental Biophysics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, Compendex, EMBASE, Environment Index, INSPEC, MEDLINE, Pollution Abstracts, Veterinary Science Database, DIALNET
  • Sayfa Sayıları: ss.261-268
  • Anahtar Kelimeler: Head and neck neoplasms, Mouth neoplasms, Radiobiology, Radiotherapy, Tooth
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

The aims of the study were to analyze the effects of therapeutic radiation on human root dentin samples from the aspect of possible alterations in crystallinity, micro-morphology, and composition. Fifty-six root dentin specimens were divided into seven groups (0, 10, 20, 30, 40, 50, and 60 Gy). Scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD) analyses were performed on pulpal surfaces of root dentin after being irradiated by 6MV photon energy. Mineral compositions, Ca/P, P/N, Ca/N ratios, and hydroxyapatite pikes were calculated. Some deuteriations on the dentin surface were observed in SEM images after 30 Gy and subsequent doses. One-way ANOVA revealed that there was no significant alteration in weight percentages of C, O, Mg, Ca, P, and N between groups. Radiation did not influence stoichiometric Ca/P, Ca/N, and P/N molar ratios. XRD analysis did not show a remarkable decline in hydroxyapatite pikes by the increasing doses. Radiotherapy changes the micromorphology of circumpulpal dentin but does not affect elemental composition and crystallinity.